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Personalized Lifestyle Medicine

About the Glastonbury Naturopathic Health Center

Dr. P New photo 2012

Dr. Helene Pulnik

RPh, MS, ND, LAc. Dipl. NCCAOM

Medical Director

Dr. Pulnik has been a healthcare provider for more than 25 years. She is a licensed acupuncturist and board-certified naturopathic physician trained in one of the five accredited schools for naturopathic medicine in North America.

Dr. Pulnik’s accreditations include:

    Doctorate in Naturopathic Medicine — College of Naturopathic Medicine at the University of Bridgeport
    Master’s degree in Human Nutrition — Nutrition Institute at the University of Bridgeport
    Bachelor's degree in pharmacy — University of Connecticut
    Registered pharmacist
    Licensed Acupuncturist, Dipl. NCCAOM
    Member — Connecticut Naturopathic Physicians Association (CNPA)

In addition, Dr. Pulnik has been on the teaching faculty at the College of Naturopathic Medicine and Acupuncture Institute at the University of Bridgeport, and has given many presentations on natural medicine.

Dr. Pulnik’s Treatment Philosophy

Naturopathic physicians are trained as primary care providers, and Dr. Pulnik has experience with conventional medicines and treatments. However, unlike conventional physicians, who listen to patients for an average of less than 30 seconds, Dr. Pulnik works with each patient to design an effective, personalized treatment plan — which is only possible after careful listening, review of your medical history, and interpretation of your symptoms.

In addition to drawing on the principles of naturopathic medicine, Dr. Pulnik utilizes Advanced Allergy Therapeutics, acupuncture, vitamin therapy, herbal medicine, homeopathic remedies, stress reduction, laboratory testing, and other natural, holistic techniques to provide patients with non-invasive modes of healing. Trained in several different areas of holistic medicine, Dr. Pulnik is able to work with patients to achieve powerful results — no matter what your affliction.

As a Naturopathic Physician and Clinical Nutritionist, Dr. Pulnik expertly prescribes dietary therapy and nutritional supplementation along with clinical and laboratory diagnosis to return you to a healthier balance.

Glastonbury Naturopathic Center and Wholistic Spa™, offering naturopathic medicine, acupuncture, and Wholistic Spa™ treatments all under one roof, is currently accepting new patients. Please contact us with any questions, to schedule an appointment, or to learn more about any of our services.

To help cover the cost of naturopathic medicine, Dr. Pulnik accepts Anthem Blue Cross, Cigna, Oxford and Connecticare Insurances.

 Charles Lerner

Dr. Charles Lerner

Chiropractor and Acupuncturist

Dr. Charles Lerner is a very accomplished Acupuncturist, who offers expert Acupuncture care for acute and chronic problems, both internal medical concerns and pain management.

His acupuncture techniques include painless needle insertion and he is familiar with a large variety of Oriental medical approaches, enabling him to choose the exact acupuncture technique that is most effective for each patient. He gentle, compassionate and treats his patients as whole beings, not symptoms or diseases.

Dr. Lerner graduated from Western States Chiropractic College in Portland, Oregon, and went on to  earn his Master's Degree in Acupuncture from Pacific College of Oriental Medicine In New York City. He donates his time and acupuncture skills each year to helping the poor and needy at the Hospital De La Familia, a missionary hospital in northwestern Guatemala.

Dr. Lerner is now accepting new Acupuncture patients at Glastonbury Naturopathic Center.


Connie BEST


Constance Jones

I-ACT & NBCHT Certified Colon Hydrotherapist
34 Years Experience


Connie Jones has been practicing Colon Hydrotherapy since 1980. She is New England's Senior Colon Hydrotherapist. Connie provides you with the highest quality of safe, comfortable, and effective colon hydrotherapy at Glastonbury Naturopathic Center, where she has been supervised by Dr. Helene Pulnik since 2003.

During her 34 years of experience, Connie has performed well over 50,000 colonics. When you enter Connie's colon hydrotherapy room, her attention is devoted to you completely. Her clients comment on her nurturing, compassionate nature and the trust and ease that they feel with her. While maintaining both professionalism and integrity, she is also great at establishing rapport. Like others she has helped, you may leave your colon hydrotherapy session remarking on the wonderful experience you've had. Your reward is a renewed sense of calm and well-being.

Connie is certified through I-ACT as an Instructor and also through the National Board for Colon Hydrotherapy. Connie was an I-ACT Board Member for seven years. She is the founder of the New England School of Colon Hydrotherapy in Boston and served as Director for six years. For twenty-four years, Connie managed Constance Jones and Associates, which administered to over 50 clients a week in the Boston area.



Donna photo  2013


Donna Grimm

Holistic R.N., M.A.

Donna is a Registered Nurse and Psychotherapist. At Glastonbury Naturopathic Center she is the Holistic Nurse. She does Non- Invasive Advanced Allergy Treatments(AAT). Through the Highly Advanced Allergy Protocol, she helps clients release their sensativity and allergy. 

She also does Advanced Biofeedback Counseling sessions, supporting the client through processing grief, anxiety, depression and/or disease.

Donna is a Holistic Educator and Raw Food Chef and presents Educational seminars on Healthy Eatting and Detoxing Your Body with the use of the Biomat and Diet.

She brings 20 years of  Holistic Nursing and Counseling experience to help clients reach their Optimal Mental and Physical Health.  Donna also does yoga every day and assists the client in their daily movement schedule.

Marianne McAllister

Marianne McAllister

Licensed Massage Therapist

After building a creative design career in the arts and corporate environment, Marianne chose to pursue a career in the health and fitness field. Her interest in massage peaked after a week-long bike ride with 2000 riders, during which she took advantage of a tent dedicated solely to massage and found pain relief and healing as well as improved performance for the next day’s ride. 

Marianne is a graduate of Connecticut Center of Massage Therapy, Newington, CT, and a member of the American Massage Therapy Association. She provides a personalized massage guided by your individual needs and preferences and through any of a suite of modalities, including Swedish,Therapeutic, deep tissue, hot stone therapy, Thai on the table, acupressure, sports massage, as well as spa body wraps.  Her training and intuition will help you relax, slow down, and reduce pain and everyday stresses — a comprehensive healing experience that goes beyond the relief of physical symptoms. 



Garyan Yip

Licensed Massage Therapist, Licensed Esthetician (NY)

 Garyan's love for skin care, massage  and wellness is on going, as she attends spa, massage  and wellness trade shows and conferences to enhance her skills in massage, facials, body treatments and waxing. She enjoys helping guests with their skin care needs, achieving desired results, and continually learning about the latest techniques of the industry. Garyan strives to give every guest the best spa experience possible. She truly believes that beauty begins from within, and that living a healthy and happy lifestyle is the key to beautiful skin.


Janice Baxter

Licensed Massage Therapist



18 School Street
Glastonbury, CT 06033
(860) 657-4105

Our Hours

Acupuncture & Naturopathic Medicine
Monday-Friday, 10-5 pm by appointment.

Colon Hydrotherapy
Monday, Wednesday and Thursday by appointment. Call for Saturday hours.

Massage Therapy at Wholistic Spa™
Tuesday 10am-5pm
Wednesday 10am-2pm
Thursday 10am-5pm
Friday 10am-8pm
Saturday 10am-1pm

By appointment.

Organic Facials at Wholistic Spa™
Tuesdays 10-5
By Appointment.


Need Directions?

Follow the link to this map for our exact location and driving directions.

Please park in the BACK of 18 School Street and use the main entrance to the office at the front of the building. The reception room is directly through the entryway.

Please do not park in the parking area to the left of 18 School Street because it is the parking area for 24 School Street.


Social Media Policy

This document outlines Glastonbury Naturopathic Center LLC, Dr. Helene Pulnik and its healthcare providers’ Policy related to use of Social Media. Please read it to understand how I conduct myself on the Internet as a Naturopathic Physician and Acupuncturist and how you can expect me to respond to various interactions that may occur between us on the Internet. If you have any questions about anything within this document, I encourage you to bring them up when we meet. As new technology develops and the Internet changes, there may be times when I need to update this policy. If I do so, I will notify you in writing of any policy changes and make sure you have a copy of the updated policy.

All information contained on this website is intended for informational and educational purposes only, and is
neither intended nor suited to be a replacement or substitute for professional medical treatment nor for professional medical advice relative to a specific medical question or condition.


I do not accept friend or contact requests from current or former patients or clients on any social networking site (Facebook, Twitter, LinkedIn, etc). I believe that adding clients as friends or contacts on these sites can compromise your confidentiality and our respective privacy. It may also blur the boundaries of our doctor/patient relationship. If you have questions about this, please bring them up when we meet and we can talk more about it. I keep a Facebook Page for my professional practice to allow people to share my blog posts and practice updates with other Facebook users. All of the information shared on this page is available on my website. Note that you are able to subscribe to the page via RSS without liking the page and without creating a visible, public link to my Page.


I publish a blog on my website and I post health and wellness news on Facebook and Twitter. I have no expectation that you as a client will want to follow my blog, Facebook, or Twitter stream.  My primary concern is your privacy. Use your own discretion in choosing whether to follow me. Note that I will not follow you back. I only follow other health professionals on Facebook and Twitter and I do not follow current or former clients on blogs, Facebook  or Twitter. My reasoning is that I believe casual viewing of clients’ online content outside of our doctor/patient relationship can create confusion. In addition, viewing your online activities without your consent and without our explicit arrangement towards a specific purpose could potentially have a negative influence on our working relationship. If there are things from your online life that you wish to share with me, please bring them into your sessions where we can view and explore them appropriately, during the office visit.


Please do not use SMS (mobile phone text messaging) or messaging on Social Networking sites such as Twitter, Facebook, or LinkedIn to contact me. These sites are not secure and I may not read these messages in a timely fashion. Do not use Wall postings, @replies, or other means of engaging with me in public online if we have an already established doctor/patient relationship. Engaging with me this way could compromise your confidentiality. It may also create the possibility that these exchanges become a part of your legal medical record and will need to be documented and archived in your chart. If you need to contact Dr. Pulnik or any of our health care practitioners between office visits or sessions, the best way to do so is by phone. Please contact the main office at 860-657-4105 during normal office hours, which are Monday Thru Saturday from 10am-5pm.. If you have a true medical emergency after office hours, please go directly to your nearest Emergency Room or call 911.


To schedule or change appointments with Dr. Pulnik or any of our health care practitioners, the best way to do so is by phone. Please contact the main office at 860-657-4105 during regular business hours, Monday - Saturday 10am-5pm.


Thank you for taking the time to review my Social Media Policy. If you have questions or concerns about any of these policies and procedures or regarding our potential interactions on the Internet, do bring them to my attention so that we can discuss them.





Facebook Fan Special Website



  • New Science shows Dark Chocolate helps prevent Obesity, Diabetes, and more! Key Chocolate Ingredients Could Help Prevent Obesity, Diabetes Improved thinking. Decreased appetite. Lowered blood pressure. The potential health benefits of dark chocolate keep piling up, and scientists are now homing in on what ingredients in chocolate might help prevent obesity, as well as type-2 diabetes. They found that one particular type of antioxidant in cocoa prevented laboratory mice from gaining excess weight and lowered their blood sugar levels. The report appears in ACS’ Journal of Agricultural & Food Chemistry. Andrew P. Neilson and colleagues explain that cocoa, the basic ingredient of chocolate, is one of the most flavanol-rich foods around. That’s good for chocolate lovers because previous research has shown that flavanols in other foods such as grapes and tea can help fight weight gain and type-2 diabetes. But not all flavanols, which are a type of antioxidant, are created equal. Cocoa has several different kinds of these compounds, so Neilson’s team decided to tease them apart and test each individually for health benefits. The scientists fed groups of mice different diets, including high-fat and low-fat diets, and high-fat diets supplemented with different kinds of flavanols. They found that adding one particular set of these compounds, known as oligomeric procyanidins (PCs), to the food made the biggest difference in keeping the mice’s weight down if they were on high-fat diets. They also improved glucose tolerance, which could potentially help prevent type-2 diabetes. “Oligomeric PCs appear to possess the greatest antiobesity and antidiabetic bioactivities of the flavanols in cocoa, particularly at the low doses employed for the present study,” the researchers state. Source: American Chemical Society
  • by Sayer Ji, Green Med Info This commonly overlooked superfood protects the body from nuclear fallout, kills a wide range of cancers, and keeps the arteries unclogged -- to name but a few, experimentally confirmed ways in which the apple awakens your inner physician. An apple a day keeps the doctor away. This age old saying has never rang with greater promise and authority than it does today. As in the modern era, doctors bring with them a battery of tests, drugs, and interventions, all of which carry unintended, adverse health risks that often outweigh their purported benefits, and are therefore best avoided whenever possible.   Also, apples are also far cheaper than doctors, and in the worst case scenario of coerced or mandatory treatment can be thrown as a non-deadly (downright nutritious) form of self-defense.   While some might take this opening aphorism as mere folk medicine fantasy, the reality is that the medicinal properties of apple are well-documented within the biomedical literature. For instance, apple consumption has been the subject of quite a few studies on colorectal cancer risk reduction. [i] [ii] [iii]  Other cancers that apple constituents have been studied to kill in pre-clinical research include: •Liver Cancer: apple juice, apple pectin and apple peel has been experimentally confirmed to kill liver cancer,[iv] •Breast Cancer: apples have been found to both prevent and to suppress mammary cancers in the animal model.[v] •Multi-Drug Resistant Cancer: carotenoids extracted from apple have been found to inhibit drug resistant cancer cell line proliferation.[vi] •Esophageal Cancer: An apple-derived procyanidin has been found to suppress esophageal cancer. [vii] •Stomach Cancer: One of the ways in which apple constituents prevent stomach cancer is through their inhibition of Helicobacter pylori, one of the main infectious agents linked to both ulcer and gastric cancer.[viii]  But apple procyanidin has also been studied for its ability to directly induce programmed cell death within stomach cancer cells.[ix] It is likely that many of the fundamental processes involved in cancer initiation and promotion are inhibited by apples and their constituents, and therefore apples may protect against far more cancers than referenced above. It appears that no matter what part of apple is studied, it has anti-tumor properties. Apple cider vinegar, for instance, has been found to contain an anti-tumor compound which results from the acetic acid fermentative process known as alpha-glycan. Another proven way in which apples reduce the risk of cancer is through their ability to remove carcinogenic radioisotopes that have accumulated in our bodies as a result of the fallout from nuclear weapons, depleted uranium munitions, and nuclear energy and disaster-associated pollution, e.g. Chernobyl and Fukushima. Post-Chernobyl, for instance, apple pectin was used to reduce Cesium-137 levels in exposed children, in some cases by over 60%.[x] From 1996 to 2007, a total of more than 160,000 "Chernobyl" children received pectin food additives. As a result, levels of Cs-137 in children's organs decreased after each course of pectin additives by an average of 30-40%.[xi] Significant reductions were noted in as short a time period as 16 days.[xii]  Apple pectin has even been found to prevent the most deadly, and entirely man-made radioisotope, Plutonium-239, from absorbing in the gastrointestinal tract of animals fed it.[xiii] We could, therefore, modernize our apple aphorism by saying "an apple a day keeps the nuclear fallout away." And truly, there are very few other substances, natural or synthetic, that have ever been found to protect against plutonium exposure. Apples, therefore, are truly super-foods in this respect. Other noteworthy "evidence-based" medicinal properties of apple include: •Diarrhea: Apple, in combination with chamomile, shortens the course of unspecific diarrhea in children.[xiv] •Hardening of the Arteries (Atherosclerosis): Preclinical research indicates that apple contains compounds which prevent the formation of plaque within the arteries.[xv] One rabbit study, for instance, found that apple juice was capable of preventing the progression of atherosclerosis in a high cholesterol diet induced model of atherosclerosis.[xvi] •Overweight: A human study found significant weight loss associated with a daily intake of three apples or three pears among overweight women.[xvii] •Anti-Aging (Brain): Apples have been found to prevent oxidative damage and impaired maze performance,[xviii]as well as decreases in cognitive performance in aging mice.[xix] Also, a study performed on mice found that apple juice actually reduced the production of pathological amyloid-beta levels (associated with Alzheimer's disease) in the mouse brain.[xx] •Bowel Inflammation: Preclinical research has found that apple procyanidins [xxi]reduces bowel inflammation.[xxii] •Vaccine-Induced Toxicity: Many natural substances, including breast milk, have been found to decrease the synthetically-produced immune reaction associated with vaccines, and their adjuvants. Apple polyphenol counts among these, and has been found to prevent cholera toxin when used as an immune stimulant within vaccines from doing as much damage than it would otherwise do. •Periodontal Disease: We all know the sensation that follows eating an apple – that astringent property, where our gums feel squeaky clean. This is due, in part, to quercetin, which is found in apples, tea and onions, for example. It bears significant antimicrobial properties.[xxiii] Apple polyphenol also protects against periodontal ligament cell destruction associated with Porphyromonas gingivalis, a pathogenic anaerobic bacteria, infection.[xxiv] •Advanced Glycation End-products (AGEs): AGEs are associated with the oxidation of blood sugars, primarily. These sugars becomes caramelized when exposed to oxidants, and then binds to cell structures, e.g. fats/proteins, causing damage. Apple leaves have been found to have significant anti-AGE activity, including the vasoconstriction associated with AGE-induced endothelial dysfunction.[xxv] •Hair Loss: Remarkably, a procyanidin, labeled B-2, from apples promotes hair growth, in the cell model.[xxvi] •Staphylococcal Infections: Apple pectin has been shown to inhibit synthesis of types A and B staphylococcal enterotoxins, which can cause profound bodily damage.[xxvii] •Influenza Infection: Over 60 years ago researchers found that the complex carbohydrates that make up apple pectin inhibit the infectivity of influenza A virus in chicken blood, as well in embryonated eggs, indicating its potential anti-influenza properties.[xxviii] The list of evidence-based therapeutic properties of apple is rather extensive. To view the full range of experimentally confirmed benefits view them here: Apple's Health Benefits. Ultimately, this research on apples indicates how important whole foods are to our overall health. Apples are not medicine, rather, they are the means by which medicines become unnecessary. It is through authentic nourishment and detoxification – both functions which are provided to us through most fruits - that we prevent and treat disease (note: these statements likely will never be evaluated or approved by the FDA, because they are true). Also, fruit are archetypally beneficial foods for the human species; we have indexed over 300 experimentally confirmed health benefits of fruit on our database so far. Our evolutionary legacy (confirmed through modern genetic testing*) indicates that our pre-human ancestors lived in a jungle setting, where fruit would have been available year round. This would, in fact, explain why we no longer synthesize vitamin c from glucose – we were so "spoiled" by the abundance of fruit available for so long that we gave up (via genetic mutation or atavism) our ability to provide it to ourselves.  Plants and animals live in symbiosis. For the same reason that our lungs take in oxygen and give off carbon dioxide (which is live-giving to plants), the fruits of these same plants provide a seed (which we help disperse), and a flesh to entice us to consume it. Fruit, therefore, is a food source that is as ancient as human origins itself. Could this be one reason why apples seem capable of these amazing feats of healing? Perhaps. Next time you crunch into a crisp, fresh, organic apple, consider all that it has to offer, not theoretically, but viscerally. Experience the joy (the word fruit, etymologically, comes from the Latin word frui, meaning ENJOY), on a first hand basis. Also, if you have never done an apple mono-diet before, consider it. It is not so much a fruit fast, as a feast. Grab a bag of organic apples, and whenever you are hungry eat one. You will be surprised by how immediate you are satiated, and how cleansing and liberating on the body the exclusive consumption of such a simple, perfect food like the apple really is. One can easily go a day or two using this approach, often with the result of feeling completely renewed and refreshed.     Resources *Note: It is a little known and under-appreciated fact that all humans are born with a serious, life-threatening genetic defect: namely, the inability to manufacture Vitamin C. This defect occurred approximately 63 million years ago, when our haplorrhini ("simple nosed") primate predecessors lost the gene (Gulnolactone oxidase pseudogene – GULOP), responsible for the manufacture of Vitamin C from glucose. The ability to synthesize Vitamin C, in fact, has been lost several times in vertebrates, e.g. in guinea pigs, some bats, some fishes, passeriform birds and in primates of the suborder Haplorrhini, which includes monkes, apes and humans. •[i] Wieslaw Jedrychowski, Umberto Maugeri. An apple a day may hold colorectal cancer at bay: recent evidence from a case-control study. Rev Environ Health. 2009 Jan-Mar;24(1):59-74. PMID: 19476292   •[ii] Wieslaw Jedrychowski, Umberto Maugeri, Tadeusz Popiela, Jan Kulig, Elzbieta Sochacka-Tatara, Agnieszka Pac, Agata Sowa, Agnieszka Musial. Case-control study on beneficial effect of regular consumption of apples on colorectal cancer risk in a population with relatively low intake of fruits and vegetables. Basic Clin Pharmacol Toxicol. 2009 Mar;104(3):262-71. Epub 2009 Jan 20. PMID: 19926998     [iii] H Deneo-Pellegrini, E De Stefani, A Ronco. Vegetables, fruits, and risk of colorectal cancer: a case-control study from Uruguay. Nutr Cancer. 1996;25(3):297-304. PMID: 8771572     •[iv], Apple's Anti-Liver Cancer Properties     •[v], Apple's Anti-Breast Cancer Properties     •[vi] Péter Molnár, Masami Kawase, Kazue Satoh, Yoshitaka Sohara, Toru Tanaka, Satoru Tani, Hiroshi Sakagami, Hideki Nakashima, Noboru Motohashi, Nóra Gyémánt, Joseph Molnár. Biological activity of carotenoids in red paprika, Valencia orange and Golden delicious apple. Phytother Res. 2005 Aug;19(8):700-7. PMID: 16177974     •[vii] Roberto Pierini, Paul A Kroon, Sylvain Guyot, Kamal Ivory, Ian T Johnson, Nigel J Belshaw. Procyanidin effects on oesophageal adenocarcinoma cells strongly depend on flavan-3-ol degree of polymerization. Mol Nutr Food Res. 2008 Dec;52(12):1399-407. PMID: 18683822     •[viii], Helicobacter Pylori and Apples     •[ix] Hiroshige Hibasami, Toshihiko Shohji, Ichirou Shibuya, Kazuko Higo, Tomomasa Kanda. Induction of apoptosis by three types of procyanidin isolated from apple (Rosaceae Malus pumila) in human stomach cancer KATO III cells. Int J Mol Med. 2004 Jun;13(6):795-9. PMID: 15138614     •[x] V B Nesterenko, A V Nesterenko, V I Babenko, T V Yerkovich, I V Babenko. Reducing the 137Cs-load in the organism of "Chernobyl" children with apple-pectin. Swiss Med Wkly. 2004 Jan 10;134(1-2):24-7. PMID: 14745664     •[xi] Vassily B Nesterenko, Alexey V Nesterenko. 13. Decorporation of Chernobyl radionuclides. Phytother Res. 2009 Apr;23(4):564-71. PMID: 20002057     •[xii] G S Bandazhevskaya, V B Nesterenko, V I Babenko, T V Yerkovich, Y I Bandazhevsky. Relationship between caesium (137Cs) load, cardiovascular symptoms, and source of food in 'Chernobyl' children -- preliminary observations after intake of oral apple pectin. Swiss Med Wkly. 2004 Dec 18;134(49-50):725-9. PMID: 15635491     •[xiii] V S Kalistratova, G A Zalikin, P G Nisimov, I B Romanova. [Study of the effect of a food additive Medetopect on metabolic kinetics of transuranic radionuclides in animal body]. Radiats Biol Radioecol. 1998 Jan-Feb;38(1):35-41. PMID: 9606404     •[xiv] Brigitta Becker, Ulrike Kuhn, Bettina Hardewig-Budny. Double-blind, randomized evaluation of clinical efficacy and tolerability of an apple pectin-chamomile extract in children with unspecific diarrhea. Arzneimittelforschung. 2006;56(6):387-93. PMID: 16889120     •[xv], Apple's Anti-Atherosclerosis Properties     •[xvi] Mahbubeh Setorki, Sedighe Asgary, Akram Eidi, Ali Haeri Rohani, Nafiseh Esmaeil. Effects of apple juice on risk factors of lipid profile, inflammation and coagulation, endothelial markers and atherosclerotic lesions in high cholesterolemic rabbits. Lipids Health Dis. 2009;8:39. Epub 2009 Oct 5. PMID: 19804641     •[xvii] Maria Conceição de Oliveira, Rosely Sichieri, Anibal Sanchez Moura. Weight loss associated with a daily intake of three apples or three pears among overweight women. Nutrition. 2003 Mar;19(3):253-6. PMID: 12620529     •[xviii] Flaubert Tchantchou, Amy Chan, Lydia Kifle, Daniela Ortiz, Thomas B Shea. Apple juice concentrate prevents oxidative damage and impaired maze performance in aged mice. Ann Clin Psychiatry. 2009 Jul-Sep;21(3):148-61. PMID: 16340085     •[xix] [No authors listed]. Apple juice concentrate maintains acetylcholine levels following dietary compromise. J Alzheimers Dis. 2006 Aug;9(3):287-91. PMID: 16914839     •[xx] Amy Chan, Thomas B Shea. Dietary supplementation with apple juice decreases endogenous amyloid-beta levels in murine brain. Int J Mol Med. 2010 Oct;26(4):447-55. PMID: 19158432     •[xxi] Naoto Yoshino, Kohtaro Fujihashi, Yukari Hagiwara, Hiroyuki Kanno, Kiyomi Takahashi, Ryoki Kobayashi, Noriyuki Inaba, Masatoshi Noda, Shigehiro Sato . Co-administration of cholera toxin and apple polyphenol extract as a novel and safe mucosal adjuvant strategy. Vaccine. 2009 Jul 30;27(35):4808-17. Epub 2009 Jun 17. PMID: 19539583     •[xxii], Apples and Bowel Inflammation     •[xxiii] F Geoghegan, R W K Wong, A B M Rabie. Inhibitory effect of quercetin on periodontal pathogens in vitro. Phytother Res. 2009 Dec 2. Epub 2009 Dec 2. PMID: 19957242     •[xxiv] Hiroaki Inaba, Motoyuki Tagashira, Tomomasa Kanda, Takashi Ohno, Shinji Kawai, Atsuo Amano. Apple- and hop-polyphenols protect periodontal ligament cells stimulated with enamel matrix derivative from Porphyromonas gingivalis. J Periodontol. 2005 Dec;76(12):2223-9. PMID: 16332233     •[xxv] Thomas Dugé de Bernonville, Sylvain Guyot, Jean-Pierre Paulin, Matthieu Gaucher, Laurent Loufrani, Daniel Henrion, Séverine Derbré, David Guilet, Pascal Richomme, James F Dat, Marie-Noëlle Brisset . Dihydrochalcones: Implication in resistance to oxidative stress and bioactivities against advanced glycation end-products and vasoconstriction. Phytochemistry. 2009 Dec 18. Epub 2009 Dec 18. PMID: 20022617     •[xxvi] A Kamimura, T Takahashi. Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study. Sci Total Environ. 2010 Feb 13. Epub 2010 Feb 13. PMID: 11841365     •[xxvii] F S Fluer, D D Men'shikov, E B Lazareva, V Ia Prokhorov, A V Vesnin. [Influence of various pectins on production of staphylococcal enterotoxins types A and B]. Zh Mikrobiol Epidemiol Immunobiol. 2007 Nov-Dec(6):11-6. PMID: 18277535     •[xxviii] R H Green, D W Woolley. INHIBITION BY CERTAIN POLYSACCHARIDES OF HEMAGGLUTINATION AND OF MULTIPLICATION OF INFLUENZA VIRUS. J Exp Med. 1947 Jun 30;86(1):55-64. PMID: 19871655    
  • What if I told you there's a simple wellness trick that only takes five minutes a day, costs nothing, and helps cleanse your body, inside and out? Dry skin brushing has a number of health benefits and is so simple to do. So how does it work? Your skin, the largest organ in the human body is an organ of elimination. One third of your body’s toxins are excreted through the skin and dry brushing helps to unclog pores and excrete toxins that become trapped in the skin. To get started, follow the simple steps below: 1. Purchase a natural (not synthetic) bristle brush with a long handle so can reach all areas of your body. 2. Get naked and stand in a bathtub or tiled surface to catch the falling skin. (It's a bit gross, I know.) 3. Begin brushing by starting at your feet and moving in long sweeping motions toward your heart. Always brush toward your heart. 4. Brush several times in each area, overlapping as you go. 5. Take care as you brush over more sensitive areas, like breasts. Your skin will become less sensitive the more you dry brush. 6. Once you've brushed your entire body, jump in the shower. (I like to alternate between the hottest water temperature I can tolerate and the coldest. This stimulates blood circulation, bringing more blood to the top layers of the skin.) 7. After getting out of the shower, pat dry skin and apply a natural fruit oil like rose hip or coconut oil. 8. Continue to dry brush your entire body every day. Twice a day is recommended for best results. Remember to clean your brush with soap and water once a week. Leave to dry in a clean, sunny spot to avoid any mildew accumulation on your brush. Try this for 30 days and see the results for yourself! Some benefits of dry skin brushing: 1. You'll exfoliate dead skin. Forget your in-shower loofah and body scrubs, this will ensure you have silky-smooth skin all year round! 2. It stimulates your lymphatic system. Dry brushing your skin will kick start your lymphatic system, which helps you remove toxins from the body. The stiffer the bristles on the brush, the better the lymphatic stimulation you’ll create. 3. Dry brushing helps to reduce cellulite. Cellulite is simply toxic materials that have accumulated in your body’s fat cells and are trapped, unable to be eliminated from the body. Forget lipo, dry skin brushing helps to break down any trapped toxins from within the body and help your body eliminate them through its usual elimination channels. 4. It unclogs pores and de-congests skin. Dry skin brushing unclogs your skins pores and helps your skin absorb more nutrients. Daily skin brushing promotes healthy, breathing skin. It's a real treat for the largest organ in our bodies!  
  • Green Vegetables Protect the Heart By Dr. Joel Fuhrman MD     Green leafy vegetables are superior to other foods in their nutrient density, and unsurprisingly, greater intake of leafy greens is associated with reduced risk of cardiovascular disease.1, 2 Greater consumption of cruciferous vegetables (a family of vegetables known for their anti-cancer effects, it includes many leafy greens such as kale, cabbage and bok choy), are similarly associated with lower risk of death from cardiovascular disease and from all causes.3 Oxidative stress is known to be a significant contributor to the development of cardiovascular disease. Our antioxidant defenses are a combination of dietary compounds and the body’s own antioxidant enzymes, and there is evidence that when we eat cruciferous vegetables, their phytochemicals signal the body to produce its own protective antioxidant enzymes, by activating a protein called Nrf2. Nrf2 is a transcription factor, a protein that can increase or decrease the expression of certain genes. Nrf2 works by binding a specific sequence present in genes called the antioxidant response element (ARE). In the presence of certain phytochemicals, Nrf2 travels to the nucleus of the cell to induce that cell to produce natural antioxidant enzymes and protect against inflammation.4, 5 Essentially, Nrf2 is a messenger through which beneficial phytochemicals from the diet turn on the body’s natural antioxidant and anti-inflammatory protection mechanisms. For example, one study on sulforaphane (a phytochemical found in broccoli) showed that once activated, Nrf2 suppresses the activity of adhesion molecules on the endothelial cell surface to prevent binding of inflammatory cells and therefore retard atherosclerotic plaque development.6 Another study showed that sulforaphane and other isothiocyanates (cruciferous vegetable phytochemicals), by activating Nrf2, blocked inflammatory gene expression and oxidative stress in endothelial cells inhibiting aging of the vascular tree.7 Sulforaphane also helps maintain the integrity of the blood-brain barrier, a vascular system that is crucial for proper brain tissue function, via activation of Nrf2.8 The point is that cruciferous vegetables are essential for excellent health and promotion of maximum lifespan. Other phytochemicals that can activate Nrf2, iunclude anthocyanins (found in berries), EGCG (found in green tea) and resveratrol (found in grapes and peanuts).5, 9, 10 Exercise may also activate Nrf2.11 In contrast, smoking suppresses the protective actions of Nrf2; human endothelial cells exposed to the blood of smokers compared to non-smokers showed decreased Nrf2 expression, reducing antioxidant defenses.12 Not surprising that smoking and green vegetables have opposite effects! Research on phytochemicals and the protective effects Nrf2 is still in its early stages, and as we learn more, we can expect exciting advances in the understanding of how phytochemicals work to promote health and extend lifespan.   References: 1. Hung HC, Joshipura KJ, Jiang R, et al: Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst 2004;96:1577-1584. 
2. Joshipura KJ, Hu FB, Manson JE, et al: The effect of fruit and vegetable intake on risk for coronary heart disease. Ann Intern Med 2001;134:1106-1114.
3. Zhang X, Shu XO, Xiang YB, et al: Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality. Am J Clin Nutr 2011;94:240-246.
4. Donovan EL, McCord JM, Reuland DJ, et al: Phytochemical activation of Nrf2 protects human coronary artery endothelial cells against an oxidative challenge. Oxid Med Cell Longev 2012;2012:132931.
5. Han SG, Han SS, Toborek M, et al: EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes. Toxicol Appl Pharmacol 2012;261:181-188.
6. Zakkar M, Van der Heiden K, Luong le A, et al: Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state. Arterioscler Thromb Vasc Biol 2009;29:1851-1857.
7. Huang CS, Lin AH, Liu CT, et al: Isothiocyanates protect against oxidized LDL-induced endothelial dysfunction by upregulating Nrf2-dependent antioxidation and suppressing NFkappaB activation. Mol Nutr Food Res 2013;57:1918-1930.
8. Zhao J, Moore AN, Redell JB, et al: Enhancing Expression of Nrf2-Driven Genes Protects the Blood Brain Barrier after Brain Injury. J Neurosci 2007;27:10240-10248.
9. Cimino F, Speciale A, Anwar S, et al: Anthocyanins protect human endothelial cells from mild hyperoxia damage through modulation of Nrf2 pathway. Genes Nutr 2013;8:391-399.
10. Ungvari Z, Bagi Z, Feher A, et al: Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol 2010;299:H18-24.
11. Muthusamy VR, Kannan S, Sadhaasivam K, et al: Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium. Free Radic Biol Med 2012;52:366-376.
12. Fratta Pasini A, Albiero A, Stranieri C, et al: Serum oxidative stress-induced repression of Nrf2 and GSH depletion: a mechanism potentially involved in endothelial dysfunction of young smokers. PLoS One 2012;7:e30291.
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